Thionyl Chloride → Benzoyl chloride, 4-(hexyloxy)-

HRID 364854

反応式

HRID 364854 の反応式
S(Cl)([Cl:3])=O.[CH2:5]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]>>[CH2:5]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([Cl:3])=[O:17])=[CH:14][CH:13]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 708344-(Hexyloxy)benzoic acid

生成物 1

HCID 170235Benzoyl chloride, 4-(hexyloxy)-収率 98%

実験手順

Thionyl chloride (485 g of 98%, 4.00 mol) was added dropwise to 300 g (1.35 mol) of 4-hexyloxybenzoic acid. The resulting mixture was refluxed under nitrogen for 2 hours. Distillation yielded 318 g (98%) of 4-hexyloxybenzoyl chloride [boiling point 149°-153° C. (7.5 mm)].

後処理

  1. temperatureThe resulting mixture was refluxed under nitrogen for 2 hours
  2. distillationDistillation

出典と根拠

ORDレコード
ord-37bb1f97559e446dbcf78a51799a51db
出典データセット
uspto-grants-1986_08
特許番号
US04606838

関連ノート

読み込み中…