Potassium Carbonate → 4-Aminocarbonylphenoxyacetic acid methylester
反応式
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[O:7])=[CH:4][CH:3]=1.Br[CH2:12][C:13]([O:15][CH3:16])=[O:14].C([O-])([O-])=O.[K+].[K+]>CN(C=O)C.O>[CH3:16][O:15][C:13](=[O:14])[CH2:12][O:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[O:7])=[CH:4][CH:3]=1参加物
6
実験手順
A mixture of p-hydroxybenzamide (3.43 g), methyl bromoacetate (2.37 ml) and K2CO3 (3.45 g) was stirred for 12 hr in 25 ml of DMF. The reaction mixture was diluted with water (150 ml); the solid was filtered, washed with water, and air dried. Crystallization from ethanol gave 3.3 g (63%) of the title compound as white crystals.
後処理
- filtrationthe solid was filtered
- washwashed with water, and air
- customdried
- customCrystallization from ethanol
出典と根拠
- ORDレコード
- ord-660078129add4fc29c165ea2d40c339c
- 出典データセット
- uspto-grants-1995_05
- 特許番号
- US05414132
反応ノート
読み込み中…