Diisopropyl Ether → 2-[4-(Diethylamino)styryl]-5-ethyl-1-propylpyridinium bromide hemihydrate

HRID 365119

反応式

[Br-:1].[CH2:2]([C:4]1[CH:5]=[CH:6][C:7]([CH3:13])=[N+:8]([CH2:10][CH2:11][CH3:12])[CH:9]=1)[CH3:3].[CH2:14]([N:16]([CH2:25][CH3:26])[C:17]1[CH:24]=[CH:23][C:20]([CH:21]=[O:22])=[CH:19][CH:18]=1)[CH3:15].N1CCCCC1.C(OC(C)C)(C)C>CO.C(O)(C)C.CCOCC>[OH2:22].[Br-:1].[CH2:25]([N:16]([CH2:14][CH3:15])[C:17]1[CH:24]=[CH:23][C:20]([CH:21]=[CH:13][C:7]2[CH:6]=[CH:5][C:4]([CH2:2][CH3:3])=[CH:9][N+:8]=2[CH2:10][CH2:11][CH3:12])=[CH:19][CH:18]=1)[CH3:26].[CH2:14]([N:16]([C:17]1[CH:18]=[CH:19][C:20]([CH:21]=[CH:13][C:7]2[CH:6]=[CH:5][C:4]([CH2:2][CH3:3])=[CH:9][N+:8]=2[CH2:10][CH2:11][CH3:12])=[CH:23][CH:24]=1)[CH2:25][CH3:26])[CH3:15].[Br-:1]

参加物

実験手順

5-Ethyl-2-methyl-1-propylpyridinium bromide (7.32 g, 0.03 mole) and 4-diethylaminobenzaldehyde (7.0 g, 0.04 mole) were refluxed for four hours in methanol (50 ml) in the presence of piperidine (1 ml) under nitrogen. On cooling and addition of ether no precipitate was obtained. The solution was evaporated to give a red oil which was dissolved in isopropanol and twice the volume of ether was added, when a red crystalline solid was obtained (5.4 g). 2 Grams were re-dissolved in isopropanol and isopropyl ether was added to give red crystals of 2-[4-(diethylamino)styryl]-5-ethyl-1-propylpyridinium bromide hemihydrate (1.6 g), melting point 165°-167° (decomposition).

後処理

temperatureOn cooling
customwas obtained
customThe solution was evaporated
customto give a red oil which
customwhen a red crystalline solid was obtained (5.4 g)

出典と根拠

ORDレコード: ord-cb54cf80e49b4a9f8b6db21eca512b2c
出典データセット: uspto-grants-1986_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04608379

反応式

参加物

反応物 4

生成物 1

試薬・触媒・溶媒 3

実験手順

後処理

出典と根拠

関連ノート