N-Methyloctadecylamine → 3-(Diphenylphosphanyl)-N-methyl-N-octadecylpropanamide

HRID 365220

反応式

HRID 365220 の反応式
C(O[C:4](=[O:20])[CH2:5][CH2:6][P:7]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)C.[CH3:21][NH:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40].C[O-].[Na+]>>[CH3:21][N:22]([CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40])[C:4](=[O:20])[CH2:5][CH2:6][P:7]([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

参加物

4

反応物 3

HCID 75539N-MethyloctadecylamineHCID 280676Propanoic acid, 3-(diphenylphosphino)-, ethyl esterHCID 10942334Sodium Methoxide

生成物 1

HCID 539331283-(Diphenylphosphanyl)-N-methyl-N-octadecylpropanamide

反応条件

温度
100 °C

実験手順

A mixture of 5.7 g ethyl-3-diphenylphosphinopropionate (9.9 mmoles), 5.1 g N-methyl-n-octadecylamine (18.0 mmoles), and 0.3 g sodium methoxide (5.6 mmoles) were first deoxygenated and then heated to 100° C. under a nitrogen atmosphere for 24 hours. The mixture was then cooled and extracted with pentane. The pentane soluble was rotovapped to an oil.

後処理

  1. customwere first deoxygenated
  2. temperatureThe mixture was then cooled
  3. extractionextracted with pentane

出典と根拠

ORDレコード
ord-742f13ee5dcc41a9afa0a9d6004cf557
出典データセット
uspto-grants-1986_08
特許番号
US04608444

関連ノート

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