Bromoacetyl chloride → 4-Bromoacetyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine
反応式
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[S:12][CH2:11][CH2:10][NH:9][CH2:8][C:7]=2[CH:13]=1.[Br:14][CH2:15][C:16](Cl)=[O:17]>C(N(CC)CC)C>[Br:14][CH2:15][C:16]([N:9]1[CH2:8][C:7]2[CH:13]=[C:3]([O:2][CH3:1])[CH:4]=[CH:5][C:6]=2[S:12][CH2:11][CH2:10]1)=[O:17]参加物
4
実験手順
7-Methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (3.0 g), triethylamine (3.1 g) and bromoacetyl chloride (3.2 g) were reacted in the same manner as in Experimental Example 1 to give 4-bromoacetyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (2.5 g).
出典と根拠
- ORDレコード
- ord-f2d9bc7a547848ad9da613d6416d1ac8
- 出典データセット
- uspto-grants-1995_05
- 特許番号
- US05416066
反応ノート
読み込み中…