Ethyl Acetoacetate → Ethyl 3-Hydroxybutyrate
反応式
[O:1]=[C:2]([CH3:9])[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5]>CO.O>[OH:1][CH:2]([CH3:9])[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5]参加物
3
実験手順
The same procedure of Example 5 is repeated with the only differences that 1.95 g of ethyl 3-oxo-butyrate were weighed and dissolved in MeOH/H2O 19/1 (v/v) and the catalyst of Example 15 was utilized. At the end of the reaction, the ethyl 3-hydroxybutyrate resulted to be equal to 91%, while the ethyl 3-dimetoxybutyrate resulted equal to 9%. The stereoinduction was >99% in favour of the antipode (S).
後処理
- customAt the end of the reaction
出典と根拠
- ORDレコード
- ord-06436ccc24a740108351f3988fd3e4b7
- 出典データセット
- uspto-grants-2000_10
- 特許番号
- US06133191
反応ノート
読み込み中…