Sodium Cyanide → 4-Chlorobenzonitrile

HRID 36782

反応式

HRID 36782 の反応式
[C-:1]#[N:2].[Na+].F[B-](F)(F)F.[Cl:9][C:10]1[CH:15]=[CH:14][C:13]([N+]#N)=[CH:12][CH:11]=1>O>[Cl:9][C:10]1[CH:15]=[CH:14][C:13]([C:1]#[N:2])=[CH:12][CH:11]=1

参加物

4

反応物 2

HCID 8929Sodium CyanideHCID 110855064-Chlorobenzene-1-diazonium; tetrafluoroboranuide

生成物 1

HCID 121634-Chlorobenzonitrile収率 75%

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

Sodium cyanide (2.94 g; 0.06 mol) was added to water and stirred. Cuprous cyanide (2.7 g; 0.03 mol) was added to the mixture stirred until it became homogeneous. 4-chlorobenzenediazonium tetrafluoroborate (5.66 g; 0.025 mol) in water (10 ml) was added to one portion. The mixture was allowed to react at room temperature. The mixture was extracted by ethyl acetate and the extract analysed by means of gas chromatography which indicated that 4-chlorobenzonitrile had been formed in 75% yield.

後処理

  1. stirringstirred until it
  2. customto react at room temperature
  3. extractionThe mixture was extracted by ethyl acetate
  4. customhad been formed in 75% yield

出典と根拠

ORDレコード
ord-e6b27fd42fc5429c84905e1158cb162b
出典データセット
uspto-grants-1995_05
特許番号
US05416235

関連ノート

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