Benzamide → 4'-Nitrobenzanilide

HRID 369491

反応式

HRID 369491 の反応式
[C:1]([NH2:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([O-:12])=[O:11]>>[N+:10]([C:13]1[CH:18]=[CH:17][C:16]([NH:9][C:1](=[O:8])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[CH:15][CH:14]=1)([O-:12])=[O:11]

参加物

3

反応物 2

HCID 2331BenzamideHCID 7416Nitrobenzene

生成物 1

HCID 769304'-Nitrobenzanilide

実験手順

According to the recently released paper in line with the direct manufacture of amide compound formed by the NASH reaction, it is reported that benzamide is reacted with nitrobenzene in the presence of TMA(OH) to isolate N-(4-nitrophenyl)benzamide, a relatively stable intermediate, and then methanol and ammonia are added to the mixture and reacted under a pressure reactor to prepare 4-nitroaniline as a final product, while regenerating benzamide (J. Org. Chem., 1993, 58(24), 6883-8; WO No. 93/24447).

後処理

  1. customformed by the NASH reaction, it

出典と根拠

ORDレコード
ord-c2591c8af2394bc5a21b9b9ce58b6387
出典データセット
uspto-grants-2000_10
特許番号
US06137010

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