Methanol → 3-(4-Pyridyl)-4-methyl-5-methoxy-pyrazole
反応式
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[N:8]=[N:9][C:10](=[O:13])[C:11]=2[CH3:12])=[CH:3][CH:2]=1.[C:14]1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.CO.N(C(OCC)=O)=NC([O-])=O>O1CCCC1>[N:1]1[CH:2]=[CH:3][C:4]([C:7]2[C:11]([CH3:12])=[C:10]([O:13][CH3:14])[NH:9][N:8]=2)=[CH:5][CH:6]=1参加物
6
反応条件
- 温度
- 2 °C
実験手順
1.5 mg of 3-(4-pyridyl)-4-methyl-5-pyrazolone, 2.3 g of triphenylphosphine and 0.27 g of methanol were placed in 30 ml of tetrahydrofuran. The mixture was cooled on an ice bath to 2° C. and 1.6 g of ethyl azodicarboxylate dissolved in 9 ml of tetrahydrofuran was added dropwise.
後処理
- additionwas added dropwise
出典と根拠
- ORDレコード
- ord-70b9a7316e8348f29b11c4f69a806619
- 出典データセット
- uspto-grants-1985_07
- 特許番号
- US04526895
反応ノート
読み込み中…