化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Tocopheryl Nicotinate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Nicotinic Acid | HCID 938 | — |
| 反応物 | DL-alpha-Tocopherol | HCID 2116 | — |
| 反応物 | Nicotinoyl chloride | HCID 82604 | — |
| 反応物 | Nicotinic anhydride | HCID 85607 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | Tocopheryl Nicotinate | HCID 27990 | — |
反応手順
More specifically, dl-α-tocopherol is reacted with a reactive derivative of nicotinic acid such as nicotinic anhydride or nicotinic chloride in the presence of a hydrochloride and pyridine, and the resulting reaction product is post-treated and purified by column chromatography, whereby pure dl-α-tocopheryl nicotinate is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04088778 |
| 出典データセット | uspto-grants-1978_05 |
| ORD ID | ord-756ef38d6ddc4036af461588bfab451a |
| 出典メモ | uspto-grants-1978_05 |