1-benzyl-3-methylurea → HCID 70628657、化合物

HRID 372161

反応式

HRID 372161 の反応式
[CH3:1][NH:2][C:3]([NH:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:4].[CH3:13]/[C:14](/[C:20]([O-:22])=[O:21])=[C:15](\C)/[C:16]([O-:18])=O.CN1CC(=O)N([CH2:31][C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)C1=O.[CH2:38](N1CC(=O)N(C)C1=O)C1C=CC=CC=1>C1(C)C(O)=CC=CC=1.CO>[CH3:1][N:2]1[C:15](=[C:14]([CH3:13])[C:20]([O:22][CH3:38])=[O:21])[C:16](=[O:18])[N:5]([CH:6]([CH2:31][C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]1=[O:4]

参加物

7

反応物 4

HCID 2502521-benzyl-3-methylureaHCID 5459894DimethylmaleateHCID 10798228HCID 10798228、化合物HCID 13572165HCID 13572165、化合物

生成物 1

HCID 70628657HCID 70628657、化合物

試薬・触媒・溶媒 2

HCID 335O-Cresol溶媒2 回HCID 887Methanol溶媒

実験手順

82 of N-methyl-N'-benzyl urea were dissolved in 230 g of cresol and 72 g of dimethylmaleate were added. After the reaction had continued for 11/2 hours at 200° C, during which 13 g of methanol were liberated, the cresol had to be distilled off. After fractional distillation, a viscous liquid with a boiling point of 193° C/0.25 Torr was obtained as the main fraction. According to gas chromatographic analysis, it consisted of an isomeric mixture of about 80% of 1-methyl-3-benzyl-hydantoin and about 20% of 1-benzyl-3-methyl-hydantoin.

後処理

  1. custom2 hours
  2. customat 200° C
  3. distillationto be distilled off
  4. distillationAfter fractional distillation
  5. customa viscous liquid with a boiling point of 193° C/0.25 Torr was obtained as the main fraction

出典と根拠

ORDレコード
ord-488570f7007046b38321e7332eabe4cf
出典データセット
uspto-grants-1978_05
特許番号
US04089860

関連ノート

読み込み中…