Water → (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl acetate
反応式
[OH:1][CH2:2][CH:3]1[CH2:7][O:6][C:5]([CH3:9])([CH3:8])[O:4]1.N1C=CC=CC=1.[C:16](OC(=O)C)(=[O:18])[CH3:17].O>ClCCl.C(OCC)(=O)C>[C:16]([O:1][CH2:2][CH:3]1[CH2:7][O:6][C:5]([CH3:9])([CH3:8])[O:4]1)(=[O:18])[CH3:17]参加物
7
実験手順
To a mixture of 4-hydroxymethyl-2,2-dimethyl-1,3-dioxolane (5.35 g) and pyridine (15.65 g) in dichloromethane (200 ml) was added acetic anhydride (20.56 g), and the mixture was stirred at ambient temperature for 12 hours. The mixture was poured into a mixture of water and ethyl acetate. The organic layer was separated, washed with saturated aqueous sodium hydrogen carbonate and brine successively, dried over magnesium sulfate, and evaporated in vacuo to give 4-acetoxymethyl-2,2-dimethyl-1,3-dioxolane (6.02 g).
後処理
- customThe organic layer was separated
- washwashed with saturated aqueous sodium hydrogen carbonate and brine successively
- dry with materialdried over magnesium sulfate
- customevaporated in vacuo
出典と根拠
- ORDレコード
- ord-d89cf0c6c2db4b6a9bf43154be9933c2
- 出典データセット
- uspto-grants-1995_05
- 特許番号
- US05420122
反応ノート
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