Thionyl Chloride → HCID 20326456、化合物
反応式
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[NH:8][C:9](=[O:16])[C:10](=[CH:14][CH:15]=2)[C:11](O)=O)=[CH:3][CH:2]=1.S(Cl)([Cl:19])=O>CCCCCC>[ClH:19].[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[NH:8][C:9](=[O:16])[C:10](=[CH:14][CH:15]=2)[CH2:11][Cl:19])=[CH:3][CH:2]=1参加物
4
実験手順
A mixture of 13 g. of 6-(4-pyridyl)-1,2-dihydro-2-oxonicotinic acid (U.S. Pat. No. 3,873,523) and 90 ml. of thionyl chloride is stirred at room temperature for 16 hours, then diluted with 250 ml. of hexane. The resulting precipitate of 6-(4-pyridyl)-1,2-dihydro-2-oxonicotinyl chloride hydrochloride is collected by filtration, washed with hexane and dried.
後処理
- additionA mixture of 13 g
- additiondiluted with 250 ml
- filtrationThe resulting precipitate of 6-(4-pyridyl)-1,2-dihydro-2-oxonicotinyl chloride hydrochloride is collected by filtration
- washwashed with hexane
- customdried
出典と根拠
- ORDレコード
- ord-9e901e3f04f341e989b448ffc6cd75c1
- 出典データセット
- uspto-grants-1978_05
- 特許番号
- US04092309
反応ノート
読み込み中…