Hydrazine hydrate (1:1) → 3-(4-Chlorophenyl)-6-hydrazinylpyridazine

HRID 372698ノート

反応式

HRID 372698 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11](Cl)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.O.[NH2:16][NH2:17]>C(O)CCC>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11]([NH:16][NH2:17])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 122575023-Chloro-6-(4-chlorophenyl)pyridazine

生成物 1

HCID 127268633-(4-Chlorophenyl)-6-hydrazinylpyridazine

試薬・触媒・溶媒 1

HCID 2631-Butanol溶媒

実験手順

A mixture of 10.0 g. of 6-(p-chlorophenyl)-3-chloropyridazine, 6.6 g. of hydrazine hydrate and 150 ml. of butanol is heated at reflux overnight. The reaction mixture is cooled and the precipitate is collected by filtration, washed with butanol and water and then dried yielding 6-(p-chlorophenyl)-3-hydrazinopyridazine.

後処理

  1. additionA mixture of 10.0 g
  2. temperatureat reflux overnight
  3. temperatureThe reaction mixture is cooled
  4. filtrationthe precipitate is collected by filtration
  5. washwashed with butanol and water
  6. customdried

出典と根拠

ORDレコード
ord-b0b02fcee0a44c98a5d896154f42a7c5
出典データセット
uspto-grants-1978_05
特許番号
US04092311

反応ノート

読み込み中…