Ammonium Hydroxide → Ethyl 3-(6-phenyl-3-pyridazinyl)carbazate

関与物質

反応手順

A mixture of 15.57 g. of ethyl 3-[6-(p-bromophenyl)-3-pyridazinyl]carbazate, 1.5 g. of 10% palladium on carbon catalyst, 200 ml. of ethanol and 60 ml. of ammonium hydroxide is shaken under 40 lb. of hydrogen pressure for 4 hours with external heating of bottle by means of a heated jacket. The reaction mixture is filtered and the filtrate concentrated to a solid which is washed with water to give 10.1 g. of cream colored crystals. Recrystallization by dissolving in ethanol and diluting with petroleum ether gave white crystals, m.p. 158°-160° C.

情報源と証拠