Allyl bromide → 5-(Prop-2-en-1-yl)thiopyrano[3,2-b]indol-4(5H)-one

反応式

[S:1]1[C:13]2[C:12]3[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=3[NH:6][C:5]=2[C:4](=[O:14])[CH:3]=[CH:2]1.[CH2:15](Br)[CH:16]=[CH2:17]>>[CH2:17]([N:6]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:12]=2[C:13]2[S:1][CH:2]=[CH:3][C:4](=[O:14])[C:5]1=2)[CH:16]=[CH2:15]

参加物

反応物 2

HCID 7841Allyl bromide

HCID 20326608Thiopyrano[3,2-b]indol-4(5H)-one

生成物 1

HCID 203266235-(Prop-2-en-1-yl)thiopyrano[3,2-b]indol-4(5H)-one

実験手順

-- By the same method as described in Example 7, 4.8 g of thiopyrano [3,2-b]-indol-4(5H)-one is alkylated with allyl bromide to give 3.9 g of product, mp 67°-68° C, after recrystallization from methylene chloride-hexane.

出典と根拠

ORDレコード: ord-9fb0f908902e46efb7ede750840d1d00
出典データセット: uspto-grants-1978_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04092328

反応ノート

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