2-Isopropylaniline → HCID 18935293、化合物

HRID 3733

反応式

HRID 3733 の反応式
[C:1](Cl)(=[O:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][S:9][C:10]1[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=1[C:12](Cl)=[O:13].[CH:21]([C:24]1[CH:30]=[CH:29][CH:28]=[CH:27][C:25]=1[NH2:26])([CH3:23])[CH3:22]>ClCCl.N1C=CC=CC=1>[CH3:22][CH:21]([C:24]1[CH:30]=[CH:29][CH:28]=[CH:27][C:25]=1[NH:26][C:1](=[O:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][S:9][C:10]1[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=1[C:12]([NH:26][C:25]1[CH:27]=[CH:28][CH:29]=[CH:30][C:24]=1[CH:21]([CH3:23])[CH3:22])=[O:13])[CH3:23]

参加物

5

反応物 2

HCID 125612-IsopropylanilineHCID 881642,2'-Dithiodibenzoyl chloride

生成物 1

HCID 18935293HCID 18935293、化合物収率 14.3%

試薬・触媒・溶媒 2

HCID 1049Pyridine溶媒HCID 6344Dichloromethane溶媒

実験手順

This compound was prepared according to the general method of Example 90 using 2,2'-dithiobisbenzoyl chloride (2.00 g, 5.83 mmol) in 50 mL of dichloromethane and 2-isopropylaniline (1.60 g, 11.6 mmol) in 13 mL of pyridine. The crude product was recrystallized twice from acetonitrile-DMF to yield 0.45 g of the title compound, mp 235°-237° C.

後処理

  1. customThis compound was prepared
  2. customThe crude product was recrystallized twice from acetonitrile-DMF

出典と根拠

ORDレコード
ord-0d887acf58894cdeab531ebdbbaba9ed
出典データセット
uspto-grants-1998_03
特許番号
US05734081

関連ノート

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