Ethanolamine → HCID 178509484、化合物
反応式
Cl[C:2]1[C:7]([C:8]#[N:9])=[CH:6][C:5]([C:10]2[CH:15]=[CH:14][N+:13]([O-:16])=[CH:12][CH:11]=2)=[CH:4][N:3]=1.[CH2:17]([CH2:19][NH2:20])[OH:18]>C(O)C>[C:8]([C:7]1[C:2]([NH:20][CH2:19][CH2:17][OH:18])=[N:3][CH:4]=[C:5]([C:10]2[CH:15]=[CH:14][N+:13]([O-:16])=[CH:12][CH:11]=2)[CH:6]=1)#[N:9]参加物
4
実験手順
5 g 2-Chloro-3-cyano-5,4'-bipyridine-1'-oxide and 8 ml ethanolamine are refluxed in 50 ml ethanol for 4 hours and then concentrated under vacuum. The residue is taken up in water, filtered off with suction, washed with water, dried at 110° C. and crystallized from ethanol/glacial acetic acid with addition of activated charcoal. Yield: 4.5 g (81.3% of the theoretical yield), with a melting point of 229° C.-231° C.
後処理
- concentrationconcentrated under vacuum
- filtrationfiltered off with suction
- washwashed with water
- customdried at 110° C.
- customcrystallized from ethanol/glacial acetic acid with addition of activated charcoal
- customYield: 4.5 g (81.3% of the theoretical yield), with a melting point of 229° C.-231° C.
出典と根拠
- ORDレコード
- ord-190aa47c2dc74cf384fd93408fbd723c
- 出典データセット
- uspto-grants-1992_11
- 特許番号
- US05162533
反応ノート
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