3-Iodoaniline → 2,2'-Dithiobis[N-(3-iodophenyl)benzamide]

HRID 3734

反応式

HRID 3734 の反応式
[C:1](Cl)(=[O:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][S:9][C:10]1[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=1[C:12](Cl)=[O:13].[I:21][C:22]1[CH:23]=[C:24]([CH:26]=[CH:27][CH:28]=1)[NH2:25]>ClCCl.N1C=CC=CC=1>[I:21][C:22]1[CH:23]=[C:24]([NH:25][C:1](=[O:19])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[S:8][S:9][C:10]2[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=2[C:12]([NH:25][C:24]2[CH:26]=[CH:27][CH:28]=[C:22]([I:21])[CH:23]=2)=[O:13])[CH:26]=[CH:27][CH:28]=1

参加物

5

反応物 2

HCID 122713-IodoanilineHCID 881642,2'-Dithiodibenzoyl chloride

生成物 1

HCID 189353092,2'-Dithiobis[N-(3-iodophenyl)benzamide]収率 7.3%

試薬・触媒・溶媒 2

HCID 1049Pyridine溶媒HCID 6344Dichloromethane溶媒

実験手順

This compound was prepared according to the general method of Example 77 using 2,2'-dithiobisbenzoyl chloride (3.00 g, 8.74 mmol) in 75 mL of dichloromethane and 3-iodoaniline (3.82 g, 17.5 mmol) in 17 mL of pyridine. The crude product was triturated with hot ethanol, filtered, and recrystallized first from water-DMF, then from ethyl acetate-ether to yield 0.45 g of the title compound, mp 184°-186° C. (dec.).

後処理

  1. customThis compound was prepared
  2. customThe crude product was triturated with hot ethanol
  3. filtrationfiltered
  4. customrecrystallized first from water-DMF

出典と根拠

ORDレコード
ord-820622bd6d264f8c8a3784a27744ca1b
出典データセット
uspto-grants-1998_03
特許番号
US05734081

関連ノート

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