ホームMCPワークベンチSkills
ホームワークベンチ通知マイページ
llms.txt · MCPガイドプライバシーポリシー · 利用規約 · サポートv1.8.0
  1. ホーム
  2. /反応

2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → N-benzylcarbazole-3,4-dicarboximide

HRID 373988
ノート
印刷プレビュー

反応式

HRID 373988 の反応式
[CH2:1]([N:8]1[C:24](=[O:25])[CH:23]2[CH:11]([CH2:12][CH2:13][C:14]3[NH:15][C:16]4[C:21]([C:22]=32)=[CH:20][CH:19]=[CH:18][CH:17]=4)[C:9]1=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.ClC1C(=O)C(C#N)=C(C#N)C(=O)C=1Cl.C(=O)([O-])[O-].[K+].[K+]>C(Cl)Cl>[CH2:1]([N:8]1[C:24](=[O:25])[C:23]2[C:22]3[C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[NH:15][C:14]=3[CH:13]=[CH:12][C:11]=2[C:9]1=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1
参加物実験手順後処理出典と根拠反応ノート

参加物

5

反応物 3

HCID 67752,3-Dichloro-5,6-dicyano-1,4-benzoquinoneHCID 11430Potassium CarbonateHCID 2865034N-benzyl-1,2,3,4-tetrahydrocarbazole-3,4-dicarboximide

生成物 1

HCID 19808688N-benzylcarbazole-3,4-dicarboximide収率 81%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

150 mg of N-benzyl-1,2,3,4-tetrahydrocarbazole-3,4-dicarboximide was dissolved in 5 ml of methylene chloride. To this solution was added 220 mg of 2,3-dichloro-5,6-dicyano-p-benzoquinone (abbreviated to hereinafter as DDQ). The mixture was stirred at room temperature for 10 minutes. Then, thereto were added 20 ml of methylene chloride and 10 ml of an aqueous 10% potassium carbonate solution. The organic layer was separated, washed with an aqueous saturated sodium chloride solution, and dried over anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure. The residue was recrystallized from n-propanol to obtain 120 mg (yield: 81%) of N-benzylcarbazole-3,4-dicarboximide as orange needles.

後処理

  1. customThe organic layer was separated
  2. washwashed with an aqueous saturated sodium chloride solution
  3. dry with materialdried over anhydrous magnesium sulfate
  4. customThe solvent was removed by distillation under reduced pressure
  5. customThe residue was recrystallized from n-propanol

出典と根拠

ORDレコード
ord-e3e7df8bc67b4d75846b73d1b43818de
出典データセット
uspto-grants-1992_11
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US05166204

反応ノート

読み込み中…

このページの内容参加物実験手順後処理出典と根拠反応ノート