Nitric Acid → HCID 14405001、化合物
反応式
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][C:5]([F:9])=[C:4]([Cl:10])[C:3]=1[OH:11].[N+:12]([O-])([OH:14])=[O:13]>C(O)(=O)C.ClCCl>[Cl:1][C:2]1[C:7]([F:8])=[C:6]([N+:12]([O-:14])=[O:13])[C:5]([F:9])=[C:4]([Cl:10])[C:3]=1[OH:11]参加物
5
実験手順
20 g of 2,6-dichloro-3,5-difluorophenol are initially introduced in 70 ml of acetic acid, and 8 g of 98% strength nitric acid are added dropwise. Stirring is subsequently continued at room temperature for 2 hours, and the mixture is taken up in 150 ml of dichloromethane and washed twice with water. After the dichloromethane has been distilled off, 18 g of product remain. Purity 94% according to GC analysis.
後処理
- washwashed twice with water
- distillationAfter the dichloromethane has been distilled off
出典と根拠
- ORDレコード
- ord-8a10768ac2cf409bbb96233cc6b7a57e
- 出典データセット
- uspto-grants-1992_11
- 特許番号
- US05166392
反応ノート
読み込み中…