Hexane → 4-(3-t-Butylureidomethyl)-1-aminomethylbenzene
反応式
[C:1]1([CH2:9][NH2:10])[CH:6]=[CH:5][C:4]([CH2:7][NH2:8])=[CH:3][CH:2]=1.CCCCCC.[C:17]([N:21]=[C:22]=[O:23])([CH3:20])([CH3:19])[CH3:18]>C(Cl)Cl>[C:17]([NH:21][C:22](=[O:23])[NH:8][CH2:7][C:4]1[CH:5]=[CH:6][C:1]([CH2:9][NH2:10])=[CH:2][CH:3]=1)([CH3:20])([CH3:19])[CH3:18]参加物
5
実験手順
To a solution of 2.7 g p-xylylenediamine in 100 ml methylene dichloride, was added slowly with stirring 10 ml of a n-hexan solution containing 990 mg t-butyl isocyanate under ice cooling. Stirring was continued at room temperature for two hours, the solvent was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography, giving 1 g of 4-(3-t-butylureidomethyl)-1-aminomethylbenzene.
後処理
- distillationthe solvent was distilled off under reduced pressure
- customthe residue was purified by silica gel column chromatography
出典と根拠
- ORDレコード
- ord-284a5578654e45f49e0ae5dd23284035
- 出典データセット
- uspto-grants-1992_11
- 特許番号
- US05166429
反応ノート
読み込み中…