Hydrazine hydrate (1:1) → HCID 15289591、化合物
反応式
[NH2:1][C:2]1[C:3]([CH3:19])=[N:4][C:5](Cl)=[C:6]([C:13](OCC)=[O:14])[C:7]=1[C:8](OCC)=[O:9].O.[NH2:21][NH2:22]>>[NH2:1][C:2]1[C:7]2[C:8](=[O:9])[NH:22][NH:21][C:13](=[O:14])[C:6]=2[CH:5]=[N:4][C:3]=1[CH3:19]参加物
3
反応条件
- 温度
- 100 °C
実験手順
To 57 mg of 3-amino-6-chloro-4,5-diethoxycarbonyl-2-methylpyridine was added 0.5 ml of hydrazine monohydrate, and the mixture was heated in a stream of nitrogen at 100° C. for 30 minutes. The solvent is distilled off, and the resultant crystals were collected by filtration with ethanol. After water was added to the crystals, the mixture was neutralized with 1N hydrochloric acid.
後処理
- distillationThe solvent is distilled off
- filtrationthe resultant crystals were collected by filtration with ethanol
- additionAfter water was added to the crystals
出典と根拠
- ORDレコード
- ord-23d374163e39458eb369e1c6a6d75ce3
- 出典データセット
- uspto-grants-1995_05
- 特許番号
- US05420275
反応ノート
読み込み中…