Hydrazine hydrate (1:1) → HCID 15289591、化合物
反応式
[NH2:1][C:2]1[C:3]([CH3:18])=[N:4][CH:5]=[C:6]([C:13](OCC)=[O:14])[C:7]=1[C:8](OCC)=[O:9].O.[NH2:20][NH2:21]>>[NH2:1][C:2]1[C:7]2[C:8](=[O:9])[NH:21][NH:20][C:13](=[O:14])[C:6]=2[CH:5]=[N:4][C:3]=1[CH3:18]参加物
3
反応条件
- 温度
- 100 °C
実験手順
To 57 mg of 3-amino-4,5-diethoxycarbonyl-2-methylpyridine was added 0.5 mL of hydrazine monohydrate, and the mixture was heated at 100° C. in a stream of nitrogen for 30 minutes. After the solvent was distilled off, the resulting crystals were collected by filtration with ethanol. Water was added to the crystals, and the mixture was neutralized with 1N hydrochloric acid, followed by collection of the crystals by filtration.
後処理
- distillationAfter the solvent was distilled off
- filtrationthe resulting crystals were collected by filtration with ethanol
- additionWater was added to the crystals
- filtrationfollowed by collection of the crystals by filtration
出典と根拠
- ORDレコード
- ord-727693d69aa2469abc25a8ff25403163
- 出典データセット
- uspto-grants-1995_05
- 特許番号
- US05420275
反応ノート
読み込み中…