3,4-Dimethoxycarbonyl-2-methoxy-6-methyl-5-nitropyridine → HCID 15289707、化合物
反応式
[CH3:1][O:2][C:3]([C:5]1[C:6]([O:19][CH3:20])=[N:7][C:8]([CH3:18])=[C:9]([N+:15]([O-])=O)[C:10]=1[C:11]([O:13][CH3:14])=[O:12])=[O:4]>C(OCC)(=O)C.[Pd]>[NH2:15][C:9]1[C:8]([CH3:18])=[N:7][C:6]([O:19][CH3:20])=[C:5]([C:3]([O:2][CH3:1])=[O:4])[C:10]=1[C:11]([O:13][CH3:14])=[O:12]参加物
4
実験手順
In 5 ml of ethyl acetate was dissolved 350 mg of 3,4-dimethoxycarbonyl-2-methoxy-6-methyl-5-nitropyridine, and 300 mg of 10% Pd-C (50% wet) was added to the solution. Catalytic reduction reaction was conducted for 4.5 hours. After the reaction mixture was dried over magnesium sulfate, the solvent was distilled off to afford an oily product.
後処理
- additionwas added to the solution
- customCatalytic reduction reaction
- dry with materialAfter the reaction mixture was dried over magnesium sulfate
- distillationthe solvent was distilled off
- customto afford an oily product
出典と根拠
- ORDレコード
- ord-c41010b4ebab483b8d14b7720d002562
- 出典データセット
- uspto-grants-1995_05
- 特許番号
- US05420275
反応ノート
読み込み中…