5,6-Diamino-1,3-dimethyluracil → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,4-dimethoxyphenyl)ethenyl)-1,3-dimethyl-, (E)-

HRID 375304

反応式

HRID 375304 の反応式
[NH2:1][C:2]1[C:3](=[O:12])[N:4]([CH3:11])[C:5](=[O:10])[N:6]([CH3:9])[C:7]=1[NH2:8].[CH3:13][O:14][C:15]1[CH:25]=[C:24]([O:26][CH3:27])[CH:23]=[CH:22][C:16]=1[CH:17]=[CH:18][C:19](O)=O>>[CH3:13][O:14][C:15]1[CH:25]=[C:24]([O:26][CH3:27])[CH:23]=[CH:22][C:16]=1/[CH:17]=[CH:18]/[C:19]1[NH:1][C:2]2[C:3](=[O:12])[N:4]([CH3:11])[C:5](=[O:10])[N:6]([CH3:9])[C:7]=2[N:8]=1

参加物

3

反応物 2

HCID 795015,6-Diamino-1,3-dimethyluracilHCID 856363-(2,4-Dimethoxyphenyl)prop-2-enoic acid

生成物 1

HCID 64488681H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,4-dimethoxyphenyl)ethenyl)-1,3-dimethyl-, (E)-収率 11%

実験手順

Substantially the same procedure as in Example 7 was repeated using 1.0 g (5.88 mmol) of 5,6-diamino-1,3-dimethyluracil and 1.35 g (6.48 mmol) of 2,4-dimethoxycinnamic acid. Then, the resultant crude crystals were recrystallized from dimethylformamide to give 221 mg (yield 11%) of Compound 90 as pale yellow grains.

後処理

  1. customThen, the resultant crude crystals were recrystallized from dimethylformamide

出典と根拠

ORDレコード
ord-4f385ec37bbe45b6b8760ea462141072
出典データセット
uspto-grants-1996_01
特許番号
US05484920

関連ノート

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