Cyanuric chloride → 4,6-dichloro-2-ethoxycarbonylmethylamino-S-triazine

HRID 375772

反応式

HRID 375772 の反応式
[N:1]1[C:8]([Cl:9])=[N:7][C:5](Cl)=[N:4][C:2]=1[Cl:3].Cl.[NH2:11][CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14].C(=O)(O)[O-].[Na+]>O1CCOCC1>[Cl:9][C:8]1[N:1]=[C:2]([Cl:3])[N:4]=[C:5]([NH:11][CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])[N:7]=1

参加物

5

反応物 3

HCID 7954Cyanuric chlorideHCID 516892Sodium BicarbonateHCID 2723640Glycine ethyl ester, hydrochloride

生成物 1

HCID 147462614,6-dichloro-2-ethoxycarbonylmethylamino-S-triazine

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

36.9 g of cyanuric chloride, 27.9 g of ethyl glycinate hydrochloride and 33.6 g of sodium bicarbonate were heated under reflux in 200 ml of dioxane for 30 minutes. At the end of this time, the dioxane was removed by distillation under reduced pressure, and a mixture of ethyl acetate and water was added to the resulting residue, after which the mixture was shaken.

後処理

  1. customAt the end of this time, the dioxane was removed by distillation under reduced pressure
  2. additiona mixture of ethyl acetate and water
  3. additionwas added to the resulting residue

出典と根拠

ORDレコード
ord-bd7a9204833e44b8adfa2e160635c080
出典データセット
uspto-grants-1996_01
特許番号
US05486556

関連ノート

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