Formaldehyde → HCID 18991206、化合物

反応式

[C:1]([C:5]1[CH:6]=[C:7](Br)[CH:8]=[C:9]([C:16]([CH3:19])([CH3:18])[CH3:17])[C:10]=1[O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])([CH3:4])([CH3:3])[CH3:2].[CH2:21]=[O:22]>>[C:1]([C:5]1[CH:6]=[C:7]([CH:8]=[C:9]([C:16]([CH3:19])([CH3:18])[CH3:17])[C:10]=1[O:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[CH:21]=[O:22])([CH3:4])([CH3:3])[CH3:2]

参加物

反応物 2

HCID 712Formaldehyde

HCID 10882840(2,6-Di-tert-butyl-4-bromophenoxy)trimethylsilane

生成物 1

HCID 18991206HCID 18991206、化合物収率 45%

実験手順

By proceeding as indicated in the procedure of Preparation VII above, starting with 10 mmol of 3,5-di-t-butyl-4-trimethylsilyloxy-bromobenzene and 15 mmol of HCHO (in the protected form of H2C(OCH3)2), one obtains (yield: 45%) 3,5-di-t-butyl-4-trimethylsilyloxy-benzaldehyde, followed by the expected product, 3,5-di-t-butyl-4-hydroxybenzaldehyde.

出典と根拠

ORDレコード: ord-af45e39ef51a45c29ee659f8040b5eec
出典データセット: uspto-grants-1996_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05487893

反応ノート

読み込み中…

参加物