Diethylamine → Benzoic Acid

HRID 375897

反応式

HRID 375897 の反応式
Cl[C:2]1[CH:10]=[CH:9][C:8](S(F)(=O)=O)=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].C(NCC)C>ClCCCl>[C:4]([OH:6])(=[O:5])[C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:2]=1

参加物

4

反応物 2

HCID 8021DiethylamineHCID 888732-Chloro-5-(fluorosulpho)benzoic acid

生成物 1

HCID 243Benzoic Acid

試薬・触媒・溶媒 1

HCID 111,2-Dichloroethane溶媒

実験手順

A mixture of 2-chloro-5-(fluorosulfonyl)benzoic acid (11.93 g, 0.05 mol), diethylamine (10.97 g, 0.15 mol) and 1,2-dichloroethane (100 mL) was refluxed for 8 hours. The reaction mixture was evaporated and the residue was dissolved in ethyl acetate. A solid was collected by filtration and the filtrate was evaporated to dryness to afford 15.5 g of 2-chloro-5-diethylaminosulfonyl)benzoic acid.

後処理

  1. temperaturewas refluxed for 8 hours
  2. customThe reaction mixture was evaporated
  3. dissolutionthe residue was dissolved in ethyl acetate
  4. filtrationA solid was collected by filtration
  5. customthe filtrate was evaporated to dryness

出典と根拠

ORDレコード
ord-498b6d423ed8427fba6d206335405625
出典データセット
uspto-grants-1996_01
特許番号
US05488055

関連ノート

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