Chlorotrimethylsilane → 5-Chloro-N-(2-propenyl)-3-(trimethylsilyl)-2-thiophenecarboxamide
反応式
[Cl:1][C:2]1[S:6][C:5]([C:7]([OH:9])=O)=[CH:4][CH:3]=1.[CH2:10]([NH2:13])[CH:11]=[CH2:12].[CH3:14][Si:15](Cl)([CH3:17])[CH3:16]>>[Cl:1][C:2]1[S:6][C:5]([C:7]([NH:13][CH2:10][CH:11]=[CH2:12])=[O:9])=[C:4]([Si:15]([CH3:17])([CH3:16])[CH3:14])[CH:3]=1参加物
4
実験手順
The title compound was prepared from 5-chloro-2-thiophenecarboxylic acid and allylamine, followed by reaction with TMSCl using the methods of Example 248 to afford 0.7 g of the title compound as a white solid. m.p. 63°-66° C.
出典と根拠
- ORDレコード
- ord-7dffa18c6eb3480c9e93f1dc23c9ad17
- 出典データセット
- uspto-grants-2000_02
- 特許番号
- USRE036562
反応ノート
読み込み中…