1,3,4,9-Tetrahydro-1,1-diethyl-6-(phenylmethoxy)pyrano[3,4-b]indole → 1,3,4,9-Tetrahydro-1,1-diethyl-6-(hydroxy)pyrano[3,4-b]indole

HRID 37706

反応式

[CH2:1]([C:3]1([CH2:24][CH3:25])[C:8]2[NH:9][C:10]3[C:15]([C:7]=2[CH2:6][CH2:5][O:4]1)=[CH:14][C:13]([O:16]CC1C=CC=CC=1)=[CH:12][CH:11]=3)[CH3:2]>[Pd].C(O)C>[CH2:24]([C:3]1([CH2:1][CH3:2])[C:8]2[NH:9][C:10]3[C:15]([C:7]=2[CH2:6][CH2:5][O:4]1)=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=3)[CH3:25]

参加物

実験手順

A mixture consisting of 10% Pd/c on charcoal (1.0 g), ethanol (125 mL), and 1,3,4,9-tetrahydro-1,1-diethyl-6-(phenylmethoxy)pyrano[3,4-b]indole (6.5 g, 0.0193 mol), of Step A, is hydrogenated at 30 psi for 18 hours. The reaction mixture is filtered and concentrated to give 5.2 g of product which is used in the next reaction without further purification.

後処理

filtrationThe reaction mixture is filtered
concentrationconcentrated

出典と根拠

ORDレコード: ord-faffd155ba4a4e639e8854ce1ae6fd92
出典データセット: uspto-grants-1995_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05420289

反応式

参加物

反応物 1

生成物 1

試薬・触媒・溶媒 2

実験手順

後処理

出典と根拠

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