Thionyl Chloride → Methyl 3-chlorocarbonyl-2,4-dichlorobenzoate
反応式
S(Cl)([Cl:3])=O.[Cl:5][C:6]1[C:15]([C:16](O)=[O:17])=[C:14]([Cl:19])[CH:13]=[CH:12][C:7]=1[C:8]([O:10][CH3:11])=[O:9]>CN(C)C=O.C1(C)C=CC=CC=1>[Cl:3][C:16]([C:15]1[C:6]([Cl:5])=[C:7]([CH:12]=[CH:13][C:14]=1[Cl:19])[C:8]([O:10][CH3:11])=[O:9])=[O:17]参加物
5
実験手順
Two drops of dimethylformamide and 11.90 g (0.1 mol) of thionyl chloride were added to a solution of 5.00 g (0.02 mol) of methyl 2,4-dichloro-3-hydroxycarbonylbenzoate and 50 ml of dry toluene. The solution was refluxed for 4 hours. After the solvent had been distilled off, 5.35 g of methyl 3-chlorocarbonyl-2,4-dichlorobenzoate were obtained.
後処理
- temperatureThe solution was refluxed for 4 hours
- distillationAfter the solvent had been distilled off
出典と根拠
- ORDレコード
- ord-93f4750ce6a54134adb0ffd9dc0de74a
- 出典データセット
- uspto-grants-2000_02
- 特許番号
- US06028035
反応ノート
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