Hydrazine hydrate (1:1) → 6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione
反応式
O.[NH2:2][NH2:3].Cl[C:5]1[N:10]([CH2:11][CH:12]([CH3:14])[CH3:13])[C:9](=[O:15])[N:8]([CH3:16])[C:7](=[O:17])[CH:6]=1>C(O)C>[NH:2]([C:5]1[N:10]([CH2:11][CH:12]([CH3:14])[CH3:13])[C:9](=[O:15])[N:8]([CH3:16])[C:7](=[O:17])[CH:6]=1)[NH2:3]参加物
4
実験手順
Hydrazine hydrate (6.5 ml) was added to a solution of 6-chloro-3-methyl-1-(2-methylpropyl)pyrimidine-2,4[1H,3H]-dione (10.0 g) in ethanol (40 ml). The mixture was heated at reflux for 5 hours, cooled to room temperature and then evaporated under reduced pressure. The residue was recrystallised from ethanol to give the subtitle compound (8.8 g).
後処理
- temperatureThe mixture was heated
- temperatureat reflux for 5 hours
- customevaporated under reduced pressure
- customThe residue was recrystallised from ethanol
出典と根拠
- ORDレコード
- ord-0babe5e48b794874b958f26057a9078b
- 出典データセット
- uspto-grants-2000_02
- 特許番号
- US06028074
反応ノート
読み込み中…