化工社化工社 化学情報印刷レポート · 研究参考用
(R)-2-azido-1-benzylethylamine → (2R)-3-Phenylpropane-1,2-diamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-2-azido-1-benzylethylamine | HCID 14802497 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | (2R)-3-Phenylpropane-1,2-diamine | HCID 12699299 | 103.3% |
反応手順
A sample of the compound from step 164d (1.2 g, 6.8 mmol) was hydrogenated (4 atm) in ethanol over 1.2 g of 10% Pd/C for 21.5 hours at room temperature. The mixture was filtered to remove the catalyst, and the solvent was removed to afford the title compound (1.055 g). MS m/z (M+H)+ : 151, MS m/z (M+NH4)+ : 168.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06028181 |
| 出典データセット | uspto-grants-2000_02 |
| ORD ID | ord-cb0c64fc139f4107a7a6cc1399c33171 |
| 出典メモ | uspto-grants-2000_02 |