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Methanol → 3,4-Dimethylanisole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | 3,4-Dimethylphenol | HCID 7249 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 3,4-Dimethylanisole | HCID 78411 | 81% |
反応手順
To 3,4-dimethylphenol(19.3 g, 0.16 mol), methanol(150 ml) and KOH(9.65 g, 0.25 mol) were added and then refluxed for 2 hrs. Methyl iodide(36.5 g, 0.25 mol) was added thereto, refluxed for 3 hours and then followed by addition of water(150 ml). The resulting mixture was extracted with ethylacetate and purified by column chromatography to obtain the titled compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06028195 |
| 出典データセット | uspto-grants-2000_02 |
| ORD ID | ord-ec61f0ce6933474899cf676405e5abcb |
| 出典メモ | uspto-grants-2000_02 |