Lithium Hydroxide → 3-Nitro-1-naphthoic acid
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([C:14]([O:16]C)=[O:15])[C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[CH:9][CH:8]=2)([O-:3])=[O:2].[Li+].[OH-]>CO.O>[N+:1]([C:4]1[CH:5]=[C:6]([C:14]([OH:16])=[O:15])[C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[CH:9][CH:8]=2)([O-:3])=[O:2]参加物
4
実験手順
To methyl 3-nitro-1-naphthoate (2.5 g, 0.011 mole) (Aldrich) in MeOH/H2O (40 ml) (1:1) was added LiOH (1.8 g, 4 equivalents). The solution was stirred overnight at room temperature. The solvent was removed under a stream of N2. The residue was dissolved in H2O and the solution acidified with concentrated HCl. The resulting precipitate was filtered, washed with H2O and dried to yield 3-nitro-1-naphthoic acid (2.18 g) as a white solid.
後処理
- customThe solvent was removed under a stream of N2
- dissolutionThe residue was dissolved in H2O
- filtrationThe resulting precipitate was filtered
- washwashed with H2O
- customdried
出典と根拠
- ORDレコード
- ord-1674374bd5754d5688a4db8ea468c333
- 出典データセット
- uspto-grants-2000_02
- 特許番号
- US06028223
反応ノート
読み込み中…