2,3,4-Trichlorobenzenesulfonyl chloride → 2,3,4-Trichloro-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide

HRID 378480

反応式

HRID 378480 の反応式
[NH2:1][C:2]1[O:6][N:5]=[C:4]([CH3:7])[C:3]=1[Br:8].[Cl:9][C:10]1[C:15]([Cl:16])=[C:14]([Cl:17])[CH:13]=[CH:12][C:11]=1[S:18](Cl)(=[O:20])=[O:19]>>[Cl:9][C:10]1[C:15]([Cl:16])=[C:14]([Cl:17])[CH:13]=[CH:12][C:11]=1[S:18]([NH:1][C:2]1[O:6][N:5]=[C:4]([CH3:7])[C:3]=1[Br:8])(=[O:20])=[O:19]

参加物

3

反応物 2

HCID 369042,3,4-Trichlorobenzenesulfonyl chlorideHCID 104875194-Bromo-3-methylisoxazol-5-amine

生成物 1

HCID 186173412,3,4-Trichloro-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide収率 66%

実験手順

2,3,4-Trichloro-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide was prepared from 5-amino-4-bromo-3-methylisoxazole and 2,3,4-trichlorobenzenesulfonyl chloride according to the procedures described in Example 30. The crude product was purified by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p.110-113° C., yield 66%.

後処理

  1. customThe crude product was purified by recrystallization from ethyl acetate/hexanes
  2. customto give a crystalline solid, m.p.110-113° C., yield 66%

出典と根拠

ORDレコード
ord-eec456e3df094707b35d9f870e4964ab
出典データセット
uspto-grants-2000_02
特許番号
US06030991

関連ノート

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