関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Morpholine | HCID 8083 | — |
| 反応物 | 4,6-Dichloropyrimidine | HCID 70943 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-(6-Chloropyrimidin-4-yl)morpholine | HCID 796070 | — |
反応手順
45.0 g (302.1 mmol) of 4,6-dichloropyrimidine are initially charged in 450 ml of water. 26.3 g (302.1 mmol) of morpholine are added, and the mixture is stirred at 90° C. for 16 h. The mixture is then cooled to 0° C., and the precipitate formed is filtered off. The precipitate is washed once with 50 ml of water and air-dried.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08524699B2 |
|---|
| 出典データセット | uspto-grants-2013_09 |
|---|
| ORD ID | ord-d1f9ab0e57eb42c6b0e421bc0e8cbff6 |
|---|
| 出典メモ | uspto-grants-2013_09 |
|---|
