3-[Hydroxy(3-methoxyphenyl)methyl)-2-oxotetrahydrofuran → 3-(3-Methoxybenzyl)-2-oxotetrahydrofuran

HRID 380087ノート

反応式

HRID 380087 の反応式
O[CH:2]([C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[CH:10]=1)[CH:3]1[CH2:7][CH2:6][O:5][C:4]1=[O:8]>C(O)C.[Pd]>[CH3:16][O:15][C:11]1[CH:10]=[C:9]([CH:14]=[CH:13][CH:12]=1)[CH2:2][CH:3]1[CH2:7][CH2:6][O:5][C:4]1=[O:8]

参加物

4

反応物 1

HCID 183672943-[Hydroxy(3-methoxyphenyl)methyl)-2-oxotetrahydrofuran

生成物 1

HCID 183673643-(3-Methoxybenzyl)-2-oxotetrahydrofuran収率 86.2%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A mixture of 3-[hydroxy(3-methoxyphenyl)methyl]-2-oxotetrahydrofuran (1.0 g) and 10% Pd/C (0.5 g) in ethanol (20 ml) was stirred under H2 for 10 hours. The catalyst was filtered off and the filtrate was evaporated in vacuo to give 3-(3-methoxybenzyl)-2-oxotetrahydrofuran (0.8 g).

後処理

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated in vacuo

出典と根拠

ORDレコード
ord-e4a510a9640f4e029356e7f2dd1100ff
出典データセット
uspto-grants-2001_10
特許番号
US06300344B1

反応ノート

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