Benzothiazole → 6-Nitrobenzothiazole
反応式
[N+:1]([O-:4])(O)=[O:2].OS(O)(=O)=O.[S:10]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[CH:11]1>>[N+:1]([C:16]1[CH:17]=[CH:18][C:13]2[N:12]=[CH:11][S:10][C:14]=2[CH:15]=1)([O-:4])=[O:2]参加物
3
反応条件
- 温度
- 25 °C
実験手順
To a 30 mL solution of 1:1 mixture of HNO3—H2SO4 was added benzothiazole (7.0 mL, 53 mmol) slowly over 1 h period at −25° C. and resulting solution was stirred for 12 h. Reaction temperature was allowed to warm up to 25° C. The reaction mixture was poured into ice water to produce a yellow precipitation which was subjected to column chromatography (CHCl3, neat) to yield 7.3 g (41 mmol, 79%) of the desired product.
後処理
- customresulting solution
- customReaction temperature
- customto produce
- customa yellow precipitation which
出典と根拠
- ORDレコード
- ord-047e4bab03954aa0a78ab5ebb53f5f2e
- 出典データセット
- uspto-grants-2001_10
- 特許番号
- US06303643B1
反応ノート
読み込み中…