Hydrochloric Acid → 3,5-Dinitrobenzoyl chloride

HRID 380719

反応式

HRID 380719 の反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([N+:13]([O-:15])=[O:14])[CH:12]=1)[C:7](O)=[O:8])([O-:3])=[O:2].S(Cl)([Cl:18])=O.[N+](C1C([N+]([O-])=O)=C(C=CC=1)C(O)=O)([O-])=O.Cl>CN(C=O)C.C(OCC)(=O)C>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([N+:13]([O-:15])=[O:14])[CH:12]=1)[C:7]([Cl:18])=[O:8])([O-:3])=[O:2]

参加物

7

反応物 4

HCID 313Hydrochloric AcidHCID 74333,5-Dinitrobenzoic acidHCID 24386Thionyl ChlorideHCID 2833272,3-Dinitrobenzoic acid

生成物 1

HCID 74323,5-Dinitrobenzoyl chloride収率 90%

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide溶媒HCID 8857Ethyl Acetate溶媒

実験手順

3,5 dinitrobenzoic acid and ethyl acetate were placed in a reaction vessel. While thionyl chloride with some drops of DMF (about double as many moles as dinitrobenzoic acid) was dropped into the reaction mixtures, the reaction mixtures were refluxed with stirring until the generation of hydrogen chloride gas stopped. The reacted solution was concentrated until a solid could be precipitated and was poured into hexane and then the precipitated solid was separated by filtration. 3,5-dinitrobenzoic chloride was obtained in a 90% yield.

後処理

  1. customthe reaction mixtures
  2. temperaturewere refluxed
  3. concentrationThe reacted solution was concentrated until a solid
  4. customcould be precipitated
  5. additionwas poured into hexane
  6. customthe precipitated solid was separated by filtration

出典と根拠

ORDレコード
ord-94448e8b87084c39ae84e619c07fa7d8
出典データセット
uspto-grants-2001_10
特許番号
US06303742B1

関連ノート

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