Methane → 2-Propanol, 1,3-bis(p-aminophenoxy)-

HRID 380726ノート

反応式

HRID 380726 の反応式
[N+:1]([C:4]1[CH:24]=[CH:23][C:7]([O:8][CH2:9][CH:10]([OH:22])[CH2:11][O:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=2)=[CH:6][CH:5]=1)([O-])=O.C>[Pd].O1CCOCC1>[NH2:19][C:16]1[CH:15]=[CH:14][C:13]([O:12][CH2:11][CH:10]([OH:22])[CH2:9][O:8][C:7]2[CH:23]=[CH:24][C:4]([NH2:1])=[CH:5][CH:6]=2)=[CH:18][CH:17]=1

参加物

5

反応物 2

HCID 297MethaneHCID 4590272-Propanol, 1,3-bis(p-nitrophenoxy)-

生成物 1

HCID 2128492-Propanol, 1,3-bis(p-aminophenoxy)-

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 312751,4-Dioxane溶媒

反応条件

温度
60 °C

実験手順

A 33.4 g (0.1 mole)-viscous liquid of 1,3-bis(4-nitrophenoxy)-2-propyl alcohol obtained in Example 6, 3 g of activated charcoal powder containing 5% Pd, and 250 ml of 1,4-dioxane were placed in a reaction vessel (hydrogenating apparatus). And the reaction mixtures were heated at 60° C. under a hydrogen atmosphere. In approximately 8 hours, 14.4 L of hydrogen was absorbed and the reaction was completed when the absorption of hydrogen stopped. Then the reacted solution was separated by filtration and the filtrate was concentrated for removing the catalyst. 27.4 g of 1,3-bis(4- aminophenoxy)-2-propyl alcohol was obtained.

後処理

  1. customwere placed in a reaction vessel
  2. customAnd the reaction mixtures
  3. custom14.4 L of hydrogen was absorbed
  4. customthe absorption of hydrogen
  5. customThen the reacted solution was separated by filtration
  6. concentrationthe filtrate was concentrated
  7. customfor removing the catalyst

出典と根拠

ORDレコード
ord-851841cbe6d844269d27de2725912d2c
出典データセット
uspto-grants-2001_10
特許番号
US06303742B1

反応ノート

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