Prochlorperazine → Apomorphine Prochlorperazine

HRID 381198

反応式

HRID 381198 の反応式
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][CH2:10][N:11]2[C:20]3[CH:21]=[C:22]([Cl:25])[CH:23]=[CH:24][C:19]=3[S:18][C:17]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]2=3)[CH2:4][CH2:3]1.[CH2:26]([OH:37])[C@H:27]([C@H:29]([C@@H:31]([C@@H](CO)O)O)O)[OH:28].C([O-])(=O)CCCCCCCCCCCCCCCCC.[Mg+2].C([O-])(=O)CCCCCCCCCCCCCCCCC>>[CH3:10][N:11]1[C@@H:12]2[CH2:17][C:16]3[CH:31]=[CH:29][C:27]([OH:28])=[C:26]([OH:37])[C:15]=3[C:14]3[C:13]2=[C:22]([CH:23]=[CH:24][CH:19]=3)[CH2:21][CH2:20]1.[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][CH2:10][N:11]2[C:20]3[CH:21]=[C:22]([Cl:25])[CH:23]=[CH:24][C:19]=3[S:18][C:17]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]2=3)[CH2:4][CH2:3]1

参加物

4

反応物 3

HCID 4917ProchlorperazineHCID 6251MannitolHCID 11177Magnesium Stearate

生成物 1

HCID 9852396Apomorphine Prochlorperazine

実験手順

Separately, prochlorperazine was added to and blended with the mannitol (Part B). Parts A and B were then combined and mixed for about 5 minutes in a V-shaped blender. Next, magnesium stearate was added to the blender, followed by continued blending for about 2 minutes.

後処理

  1. additionmixed for about 5 minutes in a V-shaped blender

出典と根拠

ORDレコード
ord-acae6ebb88f84ece86b596f4d4674f55
出典データセット
uspto-grants-2001_10
特許番号
US06306437B1

関連ノート

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