基本情報
- CAS
557-04-0- 標準SMILES
CCCCCCCCCCCCCCCCCC(=O)[O-].CCCCCCCCCCCCCCCCCC(=O)[O-].[Mg+2]- InChIKey
HQKMJHAJHXVSDF-UHFFFAOYSA-L- 分子式
- C36H70MgO4
- 平均分子量
- 591.2 g/mol
- 単同位体質量
- 590.5124524
名称と識別子
- 優先名称
- Magnesium Stearate
- IUPAC
- magnesium bis(octadecanoate)
- 現地名
- 二ステアリン酸マグネシウム
- 英語名
- Magnesium stearate
- 分子式
- C36H70MgO4
- 分子量
- 591.24
名称と別名
名称をさらに表示
データベース識別子
- CAS
557-04-0- PubChem CID
- 11177
- DTXSID
DTXSID2027208- ChEMBL
CHEMBL2106633- ChEBI
CHEBI:9254- UNII
- 70097M6I30
- EC Number
- 209-150-3
- Nikkaji
- J43.178H
物性
構造計算による物性
- 極性表面積
- 80.3 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 4
- 回転可能結合数
- 30
- 重原子数
- 41
- 形式電荷
- 0
- 複雑度
- 196
物理化学的性質
- 融点
- 200 °C · 200 °C (lit.)
- 比重(密度)
- 1.028 g/cm3 · 1.028g/cm3
- 貯蔵温度
- Inert atmosphere,Room Temperature
- 溶解性
- アルコール:不溶
- 外見
- 微粉
- 色
- 白い
- PH
- 7 · 7 (H2O) (slurry)
- 臭い (Odor)
- 白。 柔らかい油状の粉末。 味も匂いもありません。
- 水溶解度
- 不溶性
- Merck
- 14 · 14,5690
- BRN
- 3919702 · 3919702
- 安定性
- 安定。強力な酸化剤とは相容れない。
- 主な用途
- 医薬品(低分子化合物)
- 化粧品成分の機能
- 保湿固結防止増量剤着色剤
- InChI
- 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
- InChIKey
- DRJIJXNWSSRTTE-UHFFFAOYSA-M
- SMILES
- CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
- LogP
- 8.216 · 8.216 (est)
- CAS データベース
- 557 · 557-04-0(CAS DataBase Reference)
- EPAの化学物質情報
- Magnesium stearate (557-04-0)
化学的性質
化学的特性Magnesium stearate is a very fine, light white, precipitated or milled, impalpable powder of low bulk density, having a faint odor of stearic acid and a characteristic taste. The powder is greasy to the touch and readily adheres to the skin. nonflammable used in baby dusting powder(s) and as tablet lubricant.
安全と法規制
安全データ
- wgk
- -
- tsca
- TSCA listed
- rtecs
- WI4390000
- 毒性
- LD50 orally in Rabbit: > 2000 mg/kg
- hs_code
- 29157030
- risk_code
- 36/37/38
- 化審法
- (2)-611
- 安衛法
- 57,57-2
- hazard_code
- Xi
- safety_code
- 26-37/39
- ストレージクラス
- 11 - Combustible Solids
- 有毒物質データの
- 557-04-0(Hazardous Substances Data)
化学と産業
応用分野
用途滑剤、安定剤、分散剤。
用途医薬品・化粧品原料(滑沢剤)及び研究用。
用途潤滑剤、撥水剤、安定剤、増粘剤、ツヤ消剤、離型剤、加硫促進剤、グリース基材、保険機能食品、化粧品原料(清浄用化粧品、頭髪用化粧品、基礎化粧品、メークアップ化粧品、芳香化粧品、日焼け?日焼け止め化粧品、爪化粧品、アイライナー化粧品、口唇化粧品、口腔化粧品、入浴用化粧品)
用途塩化ビニル安定剤、錠剤の潤滑剤
説明Magnesium stearate, also called octa decanoic acid, magnesium salt, is a white substance, powder which becomes solid at room temperature. It has the chemical formula Mg(C18H35O2)2. It is a salt containing two equivalents of stearate (the anion of stearic acid) and one magnesium cation (Mg2+). Magnesium stearate melts at about 120 °C, is not soluble in water, and is generally considered safe for human consumption at levels below 2500 mg/kg per day.In 1979, the FDA's Subcommittee on GRAS (generally recognized as safe) Substances (SCOGS) reported, "There is no evidence in the available information on ... magnesium stearate ... that demonstrates, or suggests reasonable grounds to suspect, a hazard to the public when they are used at levels that are now current and in the manner now practiced, or which might reasonably be expected in the future.".
使用Magnesium Stearate is the magnesium salt of stearic acid which functions as a lubricant, binder, emulsifier, and anticaking agent. it is a white powder that is insoluble in water. it is used as a lubricant or die release in tableting pressed candies and is also used in sugar- less gum and mints.
一般的な説明Magnesium stearate (Mg-St) is the magnesium salt of stearic acid. Its anhydrate, dihydrate and trihydrate forms have been prepared. The tabletting of the blends of magnesium stearate and lactose granules has been described. The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined. Mg-St is widely used lubricant in pharmaceutical industry. It also plays a role in delaying the process of dissolution. Its detection in tablets by laser-induced breakdown spectroscopy has been proposed.
調製方法
Magnesium stearate is prepared either by the interaction of aqueous solutions of magnesium chloride with sodium stearate or by the interaction of magnesium oxide, hydroxide, or carbonate with stearic acid at elevated temperatures.
製造方法Magnesium stearate is created by the reaction of sodium stearate with magnesium sulfate.
上流・下流製品情報
上流原料
下流製品
サプライヤー100 社
補足説明
定義本品は、ステアリン酸(*)のマグネシウム塩であり、次の化学式で表される。参照表示名称:ステアリン酸
定義Mg(C18H35O2)2 or with one H2O. Technical grade contains small amounts of the oleate and 7% magnesium oxide, MgO.
関連反応
化合物ノート
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