Methyl iodide → (2-Acetyl-4-methylpentyl)trimethylammonium Iodide

HRID 38312

反応式

HRID 38312 の反応式
[I:1][CH3:2].[CH3:3][N:4]([CH2:6][CH:7]([CH2:11][CH:12]([CH3:14])[CH3:13])[C:8](=[O:10])[CH3:9])[CH3:5]>C(OCC)(=O)C>[I-:1].[C:8]([CH:7]([CH2:11][CH:12]([CH3:14])[CH3:13])[CH2:6][N+:4]([CH3:2])([CH3:5])[CH3:3])(=[O:10])[CH3:9]

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 534190393-((Dimethylamino)methyl)-5-methyl-2-hexanone

生成物 1

HCID 86641883(2-Acetyl-4-methylpentyl)trimethylammonium Iodide収率 68.4%

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

Iodomethane (20 g, 140.94 mmol, 2.00 equiv) was added dropwise to a solution of 3-((dimethylamino)methyl)-5-methylhexan-2-one (12 g, 70.05 mmol, 1.00 equiv) and ethyl acetate (50 mL). The solution was stirred at ambient temperature for about 16 hours., and the resulting preciptant was collected by filtration to afford the title product (15 g, yield=68%).

後処理

  1. filtration, and the resulting preciptant was collected by filtration

出典と根拠

ORDレコード
ord-279e4411a2944fb7abb24634632e5481
出典データセット
uspto-grants-2013_09
特許番号
US08524733B2

関連ノート

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