Iodine → Muconic Acid

HRID 385194

反応式

HRID 385194 の反応式
[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]\[CH:4]=[CH:5]\[C:6]([OH:8])=[O:7].II>C(#N)C>[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[C:6]([OH:8])=[O:7]

参加物

4

反応物 2

HCID 807IodineHCID 5280614(2E,4Z)-2,4-Hexadienedioic acid

生成物 1

HCID 5356793Muconic Acid収率 80%

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

A mixture containing cis,trans muconic acid (1.00 g), a catalytic amount of iodine (53 mg, 3.0 mole percent), and acetonitrile (35 ml) is heated to reflux for 11 hours. The reaction is performed in the presence of ambient light in the laboratory. After cooling to room temperature, the precipitated solid is filtered off and washed with acetonitrile. After drying under high vacuum, 0.80 g (80 percent yield) of pure trans,trans muconic acid are present as a tan-colored powder. The material obtained by this procedure from cis,trans muconic acid is identical to the material obtained from cis,cis muconic acid by the previous procedure.

後処理

  1. temperatureto reflux for 11 hours
  2. filtrationthe precipitated solid is filtered off
  3. washwashed with acetonitrile

出典と根拠

ORDレコード
ord-8fcd241a22504c1c9f488b368d06e5ab
出典データセット
uspto-grants-2013_02
特許番号
US08367858B2

関連ノート

読み込み中…