Iodine → Muconic Acid

HRID 385195

反応式

HRID 385195 の反応式
[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]\[CH:4]=[CH:5]\[C:6]([OH:8])=[O:7].II>C1COCC1>[C:1]([OH:10])(=[O:9])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[C:6]([OH:8])=[O:7]

参加物

4

反応物 2

HCID 807IodineHCID 5280614(2E,4Z)-2,4-Hexadienedioic acid

生成物 1

HCID 5356793Muconic Acid収率 84.1%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

Cis,trans-muconic acid (19 g, 133.8 mmol) is dissolved in THF (250 mL) at room temperature and a crystal of iodine (160 mg, 0.63 mmol, 0.5 mole percent) is added. The reaction is performed in the presence of ambient light in the laboratory. The reaction mixture is allowed to stir at room temperature for 5 hours and the precipitant is filtered, washed with acetonitrile and dried under reduced pressure to yield 16 g of trans,trans-muconic acid, an 84 percent yield.

後処理

  1. filtrationthe precipitant is filtered
  2. washwashed with acetonitrile
  3. customdried under reduced pressure

出典と根拠

ORDレコード
ord-3c80a27d42cb4b9c98b18e73ef195655
出典データセット
uspto-grants-2013_02
特許番号
US08367858B2

関連ノート

読み込み中…