Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate → Trimethyl 1,2,4-benzenetricarboxylate

HRID 385203ノート

反応式

HRID 385203 の反応式
[CH:1]1([C:15]([O:17][CH3:18])=[O:16])[CH:6]=[CH:5][CH:4]([C:7]([O:9][CH3:10])=[O:8])[CH2:3][CH:2]1[C:11]([O:13][CH3:14])=[O:12]>C1(C)C=CC=C(C)C=1.[Pt]>[C:15]([O:17][CH3:18])(=[O:16])[C:1]1[C:2](=[CH:3][C:4](=[CH:5][CH:6]=1)[C:7]([O:9][CH3:10])=[O:8])[C:11]([O:13][CH3:14])=[O:12]

参加物

4

反応物 1

HCID 60136166Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate

生成物 1

HCID 17159Trimethyl 1,2,4-benzenetricarboxylate収率 65%

試薬・触媒・溶媒 2

HCID 23939Platinum触媒HCID 7929M-Xylene溶媒

実験手順

Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate (200 mg, 0.78 mmol) is mixed with 305 mg of 5 percent by weight platinum on a carbon support in m-xylene (30 ml). The reaction mixture is refluxed with the reflux apparatus being open to air for 4 days. The residual platinum on carbon is then filtered off and the filtrate is concentrated down to a clear colorless gel. The desired product is obtained with a 65 percent yield. The yield is determined by GC/MS using a dodecane as an internal standard.

後処理

  1. temperatureThe reaction mixture is refluxed with the reflux apparatus
  2. filtrationThe residual platinum on carbon is then filtered off
  3. concentrationthe filtrate is concentrated down to a clear colorless gel

出典と根拠

ORDレコード
ord-6bbaf649e24e495d812865463725d1a4
出典データセット
uspto-grants-2013_02
特許番号
US08367858B2

反応ノート

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