1,1'-Carbonyldiimidazole → HCID 59526324、化合物

HRID 385966ノート

反応式

HRID 385966 の反応式
[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[C:4]([CH3:12])[N:3]=1.[C:13](N1C=CN=C1)(N1C=CN=C1)=[O:14]>CN(C)C=O.C(OCC)(=O)C>[Cl:1][C:2]1[N:3]=[C:4]([CH3:12])[C:5]([C:6]2[O:7][C:13](=[O:14])[NH:9][N:8]=2)=[CH:10][CH:11]=1

参加物

5

反応物 2

HCID 682631,1'-CarbonyldiimidazoleHCID 595262086-Chloro-2-methylnicotinohydrazide

生成物 1

HCID 59526324HCID 59526324、化合物

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide溶媒HCID 8857Ethyl Acetate溶媒

実験手順

6-Chloro-2-methylnicotinohydrazide (60 mg, 0.32 mmol) and 1,1′-carbonylbis(1H-imidazole) (58 mg, 0.36 mmol) were taken up in dimethylformamide (1.6 ml). The reaction was heated overnight to 60° C. It was then allowed to cool to room temperature, taken up in ethyl acetate, and washed with water. The organic layer was concentrated under reduced pressure to afford the title compound.

後処理

  1. temperatureThe reaction was heated overnight to 60° C
  2. washwashed with water
  3. concentrationThe organic layer was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-5fe1a4378f904037b7d8f81c20a2376a
出典データセット
uspto-grants-2013_02
特許番号
US08367706B2

反応ノート

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