Thionyl Chloride → HCID 59526066、化合物

HRID 386120ノート

反応式

HRID 386120 の反応式
[CH3:1][C:2](=[N:4][O:5][CH2:6][C:7]([OH:9])=O)[CH3:3].S(Cl)([Cl:12])=O>C1(C)C=CC=CC=1>[CH3:1][C:2](=[N:4][O:5][CH2:6][C:7]([Cl:12])=[O:9])[CH3:3]

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 79344[(2-Propanylideneamino)oxy]acetic acid

生成物 1

HCID 59526066HCID 59526066、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

To {[(1-methylethylidene)amino]oxy}acetic acid (286 g, 2.18 mol) was added 600 ml of toluene. Thionyl chloride (364 g, 3.06 mol) was added dropwise at room temperature. After the addition was complete, the reaction mixture was heated to reflux for 10 hours. Toluene and thionyl chloride were evaporated under vacuum and the residue was distilled to afford the title compound.

後処理

  1. additionAfter the addition
  2. temperaturethe reaction mixture was heated
  3. temperatureto reflux for 10 hours
  4. customToluene and thionyl chloride were evaporated under vacuum
  5. distillationthe residue was distilled

出典と根拠

ORDレコード
ord-10e3dbd5cef642c3a68a50a65e46166f
出典データセット
uspto-grants-2013_02
特許番号
US08367706B2

反応ノート

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